I've just noticed that ČD booking engine offers tickets for just over 400 CZK (about £13) for Nürnberg to Czech destinations and tickets for about 600 CZK (about £20) from Brussels for travel on various dates in the next few weeks, which undercuts Brussels-Nürnberg fares quite significantly. Unfortunately the site doesn't get to the UK. It also offers similar fares for the München-Praha ALX service but if you use DB's IC Bus or a long-distance train to get into the Czech Republic the fares are much higher.
The fares are set in euros and then converted to CZK: https://www.cd.cz/eshop/data/CenyVJE.pdf?v=20160714
The fares are set in euros and then converted to CZK: https://www.cd.cz/eshop/data/CenyVJE.pdf?v=20160714
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