Given that it is the most direct Manchester - Preston line I would suggest using it for journeys between Manchester, Preston and Lancaster, on a 397 if at the right point in the hour for end to end journeys if possible, but the intermediate stations are well worth a visit, particularly Adlington. It has the best scenery of the 4 routes and is the closest approach of the railway to Winter Hill, which can also be seen from Chat Moss and as far away as Liverpool - Southport and the CLC line. I also very much enjoy going via Westhoughton with it and Hindley some of the best kept stations I have seen and are now having their platforms lengthened for 6 car EMUs.
I appreciate that it is the L&Y main line from Liverpool Exchange but I do try to avoid the Atherton line if at all possible, however I am forced to use it on Sundays if I want to go anywhere and the last train from Manchester to Southport goes that way. The scenery is non existent and I remember it as being just trees with a few breaks in them only for scenes of dereliction. The stops render an already painfully slow route excruciating. Daisy Hill and Atherton were already much too close together without putting Hag Fold in. I wouldn’t describe the scenery Bolton - Salford Crescent as being much better though and the stops at Moses Gate, Farnworth, Kearsley and Clifton are equally painful, but at least it has the 100mph capability, EMUs and Farnworth tunnel reboring going for it that make it a bit more interesting. I wonder if it was any better pre-grouping with 40 minute expresses using Aspinall’s Flyers. I’ve noticed there are now 195s on the Atherton line so I will have to see if those are any better. I suspect the ride quality in particular won’t be.
That just proves the WCML and Chat Moss shouldn’t be used for Preston/Wigan - Manchester journeys. I would prefer a faster Liverpool - Manchester service and a Blackpool/Preston - Crewe all stops via Newton-le-Willows because there are a few missing links currently.
I have also done it via Blackburn and Bolton. The scenery is very nice that way also, but it does take a long time, especially with a long connection at Blackburn.