It would be better if we knew the scope of the "work in progress" funded by Avanti for their classic WCML services.
I suspect it is evaluation/design of a new speed profile south of Crewe/Weaver Jn/Preston, for the 80x units coming next year.
If anything more than re-signing is needed, I suspect that will be pricey and take longer to implement, and will require DfT approval (under ERMA or the new direct award now being negotiated).
TPE was/is interested in running 397s at higher speeds north of Preston.
But even though it is still First Group, I doubt they have any money to fund an upgrade of MU speeds on the northern WCML.
Then we have HS2, in which Avanti and NR are involved, but driven by HS2 Ltd and wider political issues.
HS2 will not be interested in anything south of Crewe, or doing anything much before opening to Crewe which might be around 2030.
I'm sure a lot of thought will be put in to operation of HS2 non-tilt trains (not yet ordered) on the northern WCML, maybe with significant works including deviations.
Plus maybe resignalling with ETCS.
But none of this will be decided and be "shovel ready" in less than, say, 5 years from now and NR's CP8.
So in the short term I'd expect a modest programme of MU line speed increases south of Crewe/Weaver Jn, without changing the EPS speed profile.
Everything else will be on an HS2 timescale.
But there's quite a list of full-tilt EPS locations on the southern WCML where I doubt the MU speed will match the EPS one.
They would be: Berkhamsted, Linslade, Weedon, Rugby, Atherstone, Lichfield, Armitage-Rugeley, Queensville, Whitmore, Weaver Jn (towards Liverpool).
There are other locations which might just escape an MU restriction - eg Wolverton, Norton Bridge.
Colwich-Stoke-Cheadle Hulme is an EPS route too, with no plans to change for HS2.
Conversely, Crewe-Cheadle Hulme, which will see 3tph HS2 services under HS2a, is not an EPS route and is limited to 110mph PS.