What's the voltage drop over your chosen conductor and length at 12V? I believe at 12V over a house it is significant unless you use much thicker conductors. The 12V for your lights is also not much use for USB without further conversion or would you have 3 voltages in your house?Not really when you consider what it'd be used for. With LED lighting fed at 230VAC my lighting circuit runs at about 0.5A for the whole house if I recall rightly. Without lots of transformers this would run even lower, so if it had to be increased to run at say 12V it would still not be that high.
How much does a single 12V power supply cost that is reasonably efficient over a range of currents powering 1 light (at 3 in the morning) and the whole house? What is the expected service life?
It might make sense if you have batteries locally but for a 100% grid fed property I'm not convinced. Having said that I look forward to hearing your experiences next time you have a rewire.