Whilst some of this may have been tongue in cheek, the main thing about having 2+2 seating is the intercity style layout and comfort. So suggestions that PDL passengers can have 701s etc is sort of missing the point.
As far as end doors go, I really think that people get too hung up on this. Being a frequent traveler from Hampshire to London I often travel by Southern for price reasons, and I'll usually get a seat in the 2+2 area, and I find this to be a perfectly acceptable ambience. It's not bare minimum or just satisfactory, it's actually very nice, and I'd happily do London to Edinburgh on a 2+2 377 as well. The lack of end doors does make it feel slightly less like an intercity service, but not by much, and indeed the large windows and very soft lighting even make them feel more quality than some longer distance units.
And if people really hate the idea of a totally open layout, then why not have partition doors at 1/3 and 2/3 spacing? A similar thing is managed on the 745s with success, so I don't see why the end doors are really needed at all.