There's a housing estate on the line at Bradley Fold and scrolling left from the link below, the last part to join the surviving line at Bolton also seems to be blocked.
http://binged.it/WGdNyL
There was a housing estate built on the route of Tramlink near Coombe road. They simply compulsory purchased and demolished. Indeed it was said that the occupants of one of the newly built blocks of flats got their compulsory purchase letter the day they moved in!
Some 1930s houses in Addiscombe Road also went to provide the exit from the old Woodside - Selsdon line to get to East Croydon.
As I see it the logical thing for do would be to build a triangle junction at Radcliffe, compulsory purchase the buildings in the way at Bradley Fold, run along the old trackbed to the A666 where it would cross the viaduct then turn sharp right to run alongside the A666 to the A579. Then alongside/street run on the A579 to the station and then street run along Blackhorse Street and Deansgate.
Stations at
Black Lane,
Bradley Fold,
Springfield,
Trinity Street (East Croydon style on bridge by Bolton Station entrance),
Blackhorse Street (outside bus station),
Deansgate (near Market Hall)
Possibly continue on stree to north west suburbs (eg along B6226)
One advantage over the old Picc Vic is that it would have intermediate stations so get more local support (there were no stops between Radcliffe and Bolton on Pic Vic so the locals got all the pain with no gain).
Also unlike Pic Vic Metrolink can penetrate the town centre.
However I do think a higher priority ought to be an extension from the town centre to Salford Crescent then along the Wigan via Atherton line ( tram train), turn onto the disused railway to Ellenbrook then onto the busway east of Tyldesley and then conversion of the busway to Leigh:
So
Picc,
Picc gardens,
Along Mosley street,
change junction with second city crossing to triangle north of St Peters square and stop in Princess St
Along A34 with Stop at Deansgate
Along A6 with stops at Chapel Street, University/Salford Crescent
Pendleton (reopened)
Swinton
Moorside
Walkden
Ellenbrook
Tyldesley
Leigh