According to the routing point calculator, valid destination routing points are Crewe, Runcorn or Warrington Bank Quay.
Unfortunately, while there is a direct line from Warrington Bank Quay to Acton bridge, I think all the trains on said line run non-stop to crewe so our options are via Crewe or via Runcorn.
For preston to runcorn it looks like we can use either map CP or map JK+LC
Map CP, seems to allow travel via Ormskirk and Liverpool
Maps JK+LC seems to be for travel to Runcorn Via Crewe, so not useful to us.
Unfortunately neither map combination seems to allow travel via Wigan and Liverpool.