The North Staffs line from Derby to Crewe has to be a contender for the last semaphores ever.
It's always been a Cinderella line, as it links the two major centres of the LMS - Crewe on the LNWR and Derby on the Midland. As such, the line between them has been seen as "foreign" by both rival (but forced to talk to each other) management teams. So it'll get updated only when there's something that forces the issue - such as a catastrophic level crossing incident, heaven forbid.
It nearly went a few years ago but slipped down the priority pile. I don't think it will be too long mind. They want to run more services and the current box opening hours get in the way. There's also plans from time to time to single Meir Tunnel to get bigger freight trains through too.