There's good and bad in this. Manchester gets most of what it wanted, also Sheffield southbound. Nottingham and Derby southbound are the winners, plus Warrington does rather well. I'm slightly intrigued by the South Birmingham spur, will this just enable more commuter services, or will it eventually grow?
The middle ground is the lack of clarity on Liverpool to Warrington, Lime Street is constrained and the access is already slow, more tunnels through Edge Hill won't be cheap but is probably needed, even if the rest of the route to Warrington is essentially a 100mph upgrade online. What should probably be described as Manchester Crossrail from Warrington to Standedge looks ok, not sure about the reversal in the station, but if the cost savings allow something else to happen then it's not the worst thing ever. The ECML upgrades are useful on their own, though Leeds in particular will feel let down.
So the losers are anyone travelling through platforms 13 & 14 at Manchester Piccadilly for the next 20 years. Leeds, who thought they were getting direct HS2, and specifically connections from Leeds to Sheffield and the Midlands. Sheffield, while not doing too badly southbound, doesn't get much either towards Manchester or Leeds. Runcorn, whose service levels were more dependent on being a Cheshire Parkway on the Liverpool Line.
The wildcard is the Union Connectivity Review. For Scotland, Golborne or something better, though this will surely happen as removing HS2 East puts pressure on the ECML so removing Edinburgh is more important? Chester, electrification extending to North Wales perhaps, as I assume there will be no Diesel services into London on HS2? And, will that Birmingham spur extend towards Cardiff?