Looks bad.
These trains can carry up to 10,000 tonnes of coal (typically 100 cars of 100 tonnes each), and it looks like a fair amount of that is now spread on the interstate from the derailed cars.
Some of the reports blame a broken rail for the accident, but it's too early to tell really.
There also appears to be a dispute as to who owns the bridge that collapsed, the railway or the state of Colorado.
It was a BNSF train, quite likely from the huge Powder River Basin coal area in Wyoming.