What nobody has mentioned yet is hand and grab rails. If you have a seating layout that can be altered, then you need to think about those. Particularly if the seating layout were to be changed from say an outer-suburban type with airline and/or facing seats to a metro type with longitudual seating.
One thing SWT did when it refurbished the 455 stock, chnaging the seating from low-backed 3+2 to high-backed 2+2 was to increase the number of hand and grab rails thoughout the coach. This was to encouarge standing passengers to move into the coach, so they'd have something to hold onto. It was also the reason they switched to a 2+2 seating layout, so that standing passengers in the peak had more room. In a sense it was similar to the way tube trains have moved from having some seats in a 2+2 layout to being all longitudual seating. In the peaks (and central London) it gives more standing room. Off-peak, it's generally easy to get a seat, and the same applies on the SWT 455 units. They are certainly easier to walk through than a Class 450 with 3+2 seating.
Compare this to a Southern Class 455 unit, where new seats were fitted but the original 3+2 layout was retained.
SWT also gave more room in the entrance vestibules to speed up boarding/alighting. The doors were also modified to open to their full width, something those on the Southern units do not.