The gradients are as follows:
Climb starts around just north of Skipton, and climbs at various rate (usually around 1 in 165) to just north of Bell busk and drops back done to Settle Junction, where the S&C proper starts.
It then a ruling gradient of 1 in 100, all the way to Blea moor tunnel, when it levels out for a while, although there is a small climb just north of Garsdale (Hawes Junction). The Summit is at Ais Gill (1169 ft above sea level)
http://www.youtube.com/watch?v=8X7mVOZk54M then it drops down at a ruling gradient of in in 100, toward Appleby, when it falls at a lesser rate, of between 1 in 240 to 1 in 132 all the way to Carlisle. No wonder Carlisle to Ais Gill, which is nearly 50 miles is known as the Long Drag.
The line was built as a main line, by the midland railway, so it is laid out for quite high speed. It was busiest in the early 20th century, as evidenced by the accident high on the Fells at Hawes Junction Christmas Eve in 1910, many of the engines pilot engines for use of getting steam trains over the long grades
4.6am engines 548 and 448 arrived from Aisgill
4.14am down express passed; engines 548 and 448 were then turned and parked in the branch platform line
4.36am engines247, 249, 313 and 314 arrived from Aisgill coupled together
4.41am down "fitted" goods passed; engines 247, 249, 313 and 314 were then crossed to the turntable road
4.47am engines 317, 312 and 42 arrived from Aisgill, coupled together and were crossed to the turntable road
4.49am up through goods passed
5.20am down special express passed
http://en.wikipedia.org/wiki/Hawes_Junction_rail_crash