Having worked both guarded and DOO, I’d say there’s very little in it. Largely because modern driving policies require drivers to take a slow methodical approach to door release and closure/dispatch.
I suppose the time difference is between, on one side the guard checking all doors are closed, closing the local door, giving the start signal and the driver moving off, and on the other side the driver closing the doors, checking they're closed and moving off.
4-5 seconds? It could mount up given the amount of stops on some services, and it's probably slower than the current operation on 455s. However the 701s demonstrably have better performance to mitigate against the difference, plus driver release tends to be quicker, so overall probably no difference.
In any case, as others have pointed out, it's likely that there's no intention to increase service levels in the foreseeable future beyond the current "Covid+" levels (SWR’s claim that a 10 car 701 carries over 50% more passengers than an 8 car 455 appears to signal the intent to do nothing in this respect). Shorter station dwell times will therefore not be required.