I've ridden all three types of Eurostar in the last few months, and comparing the e300 to e320 (which is a fairly close comparison, since they have the same seats, design of overhead rack, etc) the really noticeable thing is that the higher roof makes it possible to put considerably larger luggage into the overhead rack on the e320. If only the rack was wide enough, you could easily stick full-sized suitcases up there They'd stick out sideways on an e320 now, but all of the airline-cabin-luggage sized cases that most people use these days fit easily on the e320, which means you don't miss that huge luggage store at carriage end that isn't there on the e320 but is on both layouts of the 373.
I note that the e320 manages to fit storage and luggage space opposite the non-disabled toilets, and the e300 doesn't (the disabled toilet needs the wide corridor to provide enough room for a wheelchair to get to the toilet, obv). It's staff storage in some carriages and luggage in others, IIRC.
I'm not saying it would make a huge difference, but I'd bet you can get 5-10% more seats (ie one or two more rows per carriage) on a GC-gauge train than on a W10-gauge train of the same length.
Obviously, the bi-level is a much bigger difference. TGV gets 45% more seats than single level on their duplexes compared to the single-level TGVs, rather less than double, but still a lot - you need some space for the stairs up and down from the vestibule, and there are some sections that have to be single-level (e.g. wheelchair access). TGVs have power cars with no seating, but end-carriages with cabs would be normal in the UK; those would almost certainly be single level anyway (take off room for stairs at one end and a cab at the other and there just aren't enough seats left), so it would make sense to put the wheelchair spaces and accessible toilets there.
One big advantage of buying the classic compatibles first is that the UK could get some indication of the actual popularity of the HS2 services. If the London-Birmingham services are filling up 8-car trains, then they can be doubled up; if those are filling, then bi-level captive trains (or even double-length units so you don't waste space on the middle cabs) could be put in the Phase 2 order. If demand isn't high enough, then the Phase 2 order could be single-level captives or classic compatibles.