The 442 is an excellent regional express EMU. It is quiet, it is (or was before they ruined it) comfortable and it's an excellent place to be for a 1-2 hour journey to the capital. For Weymouth to Waterloo there is simply no train on the network better suited than a properly refurbished Class 442.
Unfortunately, the list of routes for which they are well suited starts and ends with the single line they were designed for - Weymouth to Waterloo. If there is no way for them to go back onto the Weymouth to Waterloo services then as outstanding as they are and as much of a shame it will be, there is only one place for them and that's the history books.
It's a shame as we seem to have forgotten how to build a decent regional express unit since the 442, 158 and 159. Everything since has been less well suited to regional express work, especially with the obsession with 2/3 doors.