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The Leamside line is a good shout, but it depends on what you want it reopened for. A fast diversion for long distance trains to avoid the Durham curves/ congestion? A "local" service to connect Washington-area to the railway? A two-track line can't be both. And any diversion of stopping services to use a Washington station (etc) may mean a reduction in service to Durham
Self contained lines to existing stations with spare capacity are good too, like a Blyth - Newcastle service.
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To me the Leamside line would be used as a diversionary route for ECML emergencies, but more importantly as a heavy freight route, coupled with an upgrade of the Ferryhill-Stillington-Eaglescliffe-Northallerton route. This would allow any freight form Tyne Dock (and oils from Jarrow) to access the four track section of the ECML south of Northalelrton towards York without blocking up the (basically) two track Newcastle-Northallerton section. You would need some work on the junctions at Pelaw, perhaps a new cord from the down Sunderland to the up Leamside. An added benefit would be to take freight traffic off the coast route, allowing for more passenger trains. It may also be possible to route some of the fright form further north on the ECML this way to increase passenger paths south of Newcastle. It has also stuck me as strange that this line runs very close to the Nissan plant, yet Nissan send nothing out by rail, not even to the nearby Port of Tyne! Perhaps this could be addressed at the same time. There is also a massive Asda distribution centre right next door. Again an opportunity for a service perhaps.
Passenger wise (southern end) you could run a Newcastle -Middlesbrough (or Stockton) service via this route, adding in new stations at say sedgefield and Ferryhill. Although i would suggest that a more sensible option would be a Nexus metro style service from Newcastle to Fencehouses with stations at say Penshaw, Washington and Ulsworth. There are suggestions for a parkway style station at Belmont near Durham and a new station at Gateshead East but both seems unrealistic ( unless NR reopen the whole line to passengers)
However, I cant see a reopening anytime soon (which saddens me immensely) for the following reasons:
1) The condition of Victoria Viaduct between Penshaw and Washington
2) reinstallation of signalling infrastructure
3) Condition/replacement of track infrastructure (that which has not been nicked!)
4) Finance (There is a report I have seen from around 2007/2008 by the old TWPE that costed Leamside/Stillington upgrade at something like £65-85m!)
In fact I can see NR taking the track assets out and simply protecting the route from development. Unfortunately there wont be a reopening any time soon!
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As an edit - i also agree that the Blyth and Tyne route should be reopened to passengers.