BR introduced HSTs on largely or entirely sub-125mph routes, the West of England and Midland Mainline services, as they knew that the improved levels of comfort and passenger amenities coupled with the much improved journey times brought about by the rapid acceleration of the HSTs would do much to attract additional passengers to rail. HSTs were also originally earmarked for routes with 90 - 100mph maximum speeds, such as Transpennine North and Edinburgh - Glasgow.
Well the MML received its HSTs second hand from the ECML... at which point it was the most suitable route remaining that had not already received them. It was either send them there or to the sidings.
The reason that the HSTs were not deployed on TPE North and Edinburgh-Glasgow was that it was decided it was not worth it.
Were West of England services even using Mark 2 Aircons at the time the HSTs were introduced? I don't imagine mark 1s could hope to stand up to Mark 3s in comfort terms. While I do believe that a Turbostar carriage has a good chance of doing so.
You are now considering employing outer suburban/medium distance regional DMUs on routes that had HSTs deployed on them right from the very beginning? Against the principles that BR employed in selecting routes for the deployment of HSTs, this sounds like the ultimate in cost cutting as far as it can go.
No, the ultimate in cost cutting would involve no first class and 3+2 seating.
The fact remains that the only place it would lose time against a HST is possibly east of Reading and that in the Cornish section of the route that is so slow, its superior low speed acceleration may allow it to beat said HST.
An 8 coach Turbostar is also far cheaper to operate than said HST.
People want the train to arrive on time, to be air conditioned, to be reasonably quiet and for it to have WiFi/plug sockets on a long journey, a Turbostar does or can be made to fulfil all of these requirements.