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Omicron variant and the measures implemented in response to it

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Snow1964

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106,122 reported cases today, prepare for bedlam...

and how many have colds, or flu, or sniffs and sneezes etc

nobody bothers to do tests or collect data, so don’t really know if 106,122 is a problem, not that big a deal if not making people seriously ill

Nationally they are relatively flat, the problem is in London they are going up, now with 301 daily admissions in the last 24 hours. This matters because some reports suggest this rate is being used as a benchmark for future restrictions, if they exceed 400. This is despite the fact they peaked at nearly 1000 daily admissions in London last winter, and of course not everyone in hospital with covid actually went there with it.

The latest hospital figures are 8008 in hospital with covid

But the mechanical ventilation has dropped to 849 (it has been falling for 7 weeks from over 1000 in early November)

So suggests volume up slightly, but less severe cases
 
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Freightmaster

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106,122 reported cases today, prepare for bedlam...
...but if cases were "doubling every 1.9 days" as was claimed a couple of weeks ago
(and Omicron has become the dominant variant in the UK), we should by rights be
around the million cases/day mark now, so surely 106k is ten times better than the
'experts' forecasted? ;)




MARK
 

duncanp

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...but if cases were "doubling every 1.9 days" as was claimed a couple of weeks ago
(and Omicron has become the dominant variant in the UK), we should by rights be
around the million cases/day mark now, so surely 106k is ten times better than the
'experts' forecasted? ;)




MARK

Ssssshhhh!!!!!

Don't let facts get in the way of fearmongering!! <D :D
 

brad465

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Some more positive news, we do have official data confirmation that Omicron is milder than Delta, with Omicron cases 80% less likely to be admitted to hospital than previous variants, from studies of the situation in South Africa and Denmark:


A lower share of people infected with the Omicron coronavirus variant are likely to require hospital treatment compared with cases of the Delta strain...

There is caution advised about higher transmissibility leading to more hospitalisations, but an 80% reduction arguably gives plenty of cushion.

The BBC are now reporting similar, which is the first time I recall them doing so, even though other sources have earlier on since Omicron's emergence:


The wave of Omicron appears to be milder according to preliminary studies published in the UK and South Africa.
Early evidence suggests fewer people are needing hospital treatment - potentially around a two-thirds reduction - than with other variants.
However, the Scottish study is based on very few cases and had few people over 65, who are most at risk.
And the concern remains that even if Omicron is milder, the sheer number of cases could overwhelm hospitals.

The study in Scotland has been tracking coronavirus and the number of people ending up in hospital.
It said that if Omicron behaved the same as Delta then they would expect around 47 people to have been admitted to hospital already. At the moment there are only 15.
Dr Jim McMenamin, the national Covid-19 incident director at Public Health Scotland, described it as a "qualified good news story".
He said the data was "filling in a blank" about protection against hospitalisation, but cautioned it was "important we don't get ahead of ourselves".
The Omicron variant is spreading incredibly quickly and the number of confirmed cases reported in a single day in the UK has now exceeded 100,000.
The study has been shared with the World Health Organization and the UK government's science advisers.
Prof Mark Woolhouse, from the University of Edinburgh, said: "An individual infection could be relatively mild for the vast majority of people, but the potential for all these infections to come at once and put serious strain on the NHS remains."
Meanwhile, another study in South Africa also points to people being less likely to need hospital treatment for Omicron.
It showed people were 70-80% less likely to need hospital treatment, depending on whether Omicron is compared to previous waves, or other variants currently circulating.
However, it suggested there was no difference in outcomes for the few patients that ended up in hospital with Omicron.
"Compellingly, together our data really suggest a positive story of a reduced severity of Omicron compared to other variants," said Prof Cheryl Cohen of the National Institute for Communicable Diseases, in South Africa.
It is still unclear whether the Omicron variant is fundamentally milder or is appearing milder as we now have far more immunity.
The UK Health Security Agency is expected to publish early real-world data on Omicron soon, which could give indications on the variant's severity.
 
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yorkie

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Very encouraging data out of South Africa. A study released by NICD shows South Africans contracting COVID-19 in the current fourth wave of infections are 80% LESS likely to be hospitalized if infected with Omicron compared with other [variants].
It is IMPORTANT to note severity of disease in humans is NOT determined only by virus replication but also by the host immune response to the infection.
Compared to Delta infections in South Africa between April and November, Omicron infections are associated with a 70% LOWER risk of severe disease.
Original sources for the above:

https://bloomberg.com/news/articles/2021-12-22/omicron-has-80-lower-risk-of-hospitalization-new-study-shows
https://medrxiv.org/content/10.110

U.K. government scientists are set to conclude that Omicron is causing a milder disease than the Delta strain in most Britons. The U.K. Health Security Agency is due to publish its early real-world data on the severity of the disease this week.
The most encouraging news in the early data is that Britons who fall sick with Omicron are LESS likely to become severely ill than those who caught Delta. More people are likely to have a mild illness with less serious symptoms- probably in part due to Britain’s large number of
vaccinated and previously infected people, and possibly because Omicron may be intrinsically milder. Chief Medical Officer Chris Whitty has previously cautioned against too much optimism based on the initial optimistic signs from South Africa in the past few weeks.
However, the UKHSA’s view after studying cases in Britain is that Omicron is indeed usually less severe than Delta. Important Caveat. While Omicron seems to be milder overall, the UKHSA has found it is not necessarily mild enough to avoid large numbers of hospitalizations.
So, more good news as it looks increasingly likely that Omicron is indeed a less virulent variant compared to Delta, and we may reach a point in a matter of days where Chris Whitty and the Government might actually admit it.

But of course many more people are catching the virus now and therefore the fact it is milder can potentially offset the increase in numbers. The big unknown is whether the numbers infected will be so much higher that any decrease in virulence isn't enough to cause hospitals to be overwhelmed, but I am hopeful that won't happen. We are a very long way from the hospitalisation rates last winter so we'd need an incredible increase in the number daily infections to reach those levels and that does not seem likely to me.

The BBC are now reporting similar, which is the first time I recall them doing so, even though other sources have earlier on since Omicron's emergence:
Blimey, even the BBC are admitting it! :o

Edit: looks like the BBC are not quite doing so yet; they start by referring to the "Omicron wave" being milder and then go on to say:
It is still unclear whether the Omicron variant is fundamentally milder or is appearing milder as we now have far more immunity.
But as others have said, if the Omicron variant was not fundamentally milder, why did South Africa report suddenly milder cases from the time when Omicron became dominant there, and why is a similar thing happening here a few weeks later?

Of course our immunity is getting greater all the time as more people get vaccinated and infected, and this is going to have the effect of reducing hospitalisations and deaths, and we have seen this gradually taking effect over a long period of time. But Omicron has caused a step change in hospitalisations that surely cannot be explained by immunity alone.
 
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ChrisC

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Hospitalisations up 2.3% on week ago

Deaths down 2.7% on a week ago
The number of deaths have been slowly falling for the last 6 weeks and are now, after quite a rise during October, no higher than they were back in August. It is probably the booster jabs that have been helping this slow fall.

It rather concerned me that these last few days that the media seems to be focusing on infection rates and hospital admissions in London boroughs like Lambeth. The rates are rapidly rising in Lambeth but the population is not typical of the rest of the country. Lambeth has one of the youngest populations in the country and also one of the lowest percentage of people who have been vaccinated. Locking down the whole country because of what is now happening in Lambeth would have been like locking down London because of what was happening in Leicester or Bolton.
 

Nicholas Lewis

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106,122 reported cases today, prepare for bedlam...
There is a degree of catch up going on though some as old as 7 days ago which is unusual but could be home administered PCR tests that have been posted getting delayed with Xmas mail. The trend is clearly plateauing though but whether that means people aren't risking getting tested before Xmas or the system is bumping up against capacity is a potential unknown. Of course given the govt and media publicity we've had a shadow lockdown has in effect taken place so that will have provided some transmission moderation.

1640195843890.png
 

Nicholas Lewis

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The number of deaths have been slowly falling for the last 6 weeks and are now, after quite a rise during October, no higher than they were back in August. It is probably the booster jabs that have been helping this slow fall.

It rather concerned me that these last few days that the media seems to be focusing on infection rates and hospital admissions in London boroughs like Lambeth. The rates are rapidly rising in Lambeth but the population is not typical of the rest of the country. Lambeth has one of the youngest populations in the country and also one of the lowest percentage of people who have been vaccinated. Locking down the whole country because of what is now happening in Lambeth would have been like locking down London because of what was happening in Leicester or Bolton.
Yes there was a case spike up in Lambeth but is already waning. The media still fail to grasp that the virus runs out of people quicker if the spike up is steep.

1640196472704.png
 

philosopher

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It rather concerned me that these last few days that the media seems to be focusing on infection rates and hospital admissions in London boroughs like Lambeth. The rates are rapidly rising in Lambeth but the population is not typical of the rest of the country. Lambeth has one of the youngest populations in the country and also one of the lowest percentage of people who have been vaccinated. Locking down the whole country because of what is now happening in Lambeth would have been like locking down London because of what was happening in Leicester or Bolton.
Lambeth not only has a very young population, it also tends to attract young people whom are particularly keen on going out, socialising and generally partying, activities that are all conducive to Covid spread. Clapham, Brixton and to a lesser extent Streatham, which are all the London Borough of Lambeth, in particular attracts this crowd. If you look at the UK Covid dashboard, wards in the Clapham and Brixton areas now typically have cases above 3000 per 100,000.
 

brad465

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Lambeth not only has a very young population, it also tends to attract young people whom are particularly keen on going out, socialising and generally partying, activities that are all conducive to Covid spread. Clapham, Brixton and to a lesser extent Streatham, which are all the London Borough of Lambeth, in particular attracts this crowd. If you look at the UK Covid dashboard, wards in the Clapham and Brixton areas now typically have cases above 3000 per 100,000.
Not to mention that "anytime you're Lambeth way, any evening any day, you'll find them all, doing the Lambeth walk...everything's free and easy, do as you darn well pleasey..."

(Hides behind parapet)
 

Bayum

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A "third primary" dose is given to people who are immunocompromised because of a belief that they need three doses to derive the benefit two doses gives to the general population.

The third dose is considered part of their original course (just like the two doses other people received), rather than a booster dose. They then receive a booster dose at the usual interval following their third dose.

I don't believe there is such a thing as a "fourth primary" dose - outside of some very specific situations (e.g. Novavax trial participants who opted for revaccination with Pfizer to travel abroad, and then got a booster) nobody in the UK should have received five doses of vaccine.

In any case, eligibility to keep a PCR test at home and receive antivirals by post is much wider than those who received third primary doses.
Do you have any evidence to suggest that immunsuppressed patients do gain a response based on non-MRNA vaccines? Blood tests and lots of data worldwide suggests the opposite. Those we received their third ‘primary’ dose are being invited for their second within the three month period - was six as beforehand.
 

yorkie

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Do you have any evidence to suggest that immunsuppressed patients do gain a response based on non-MRNA vaccines? Blood tests and lots of data worldwide suggests the opposite. Those we received their third ‘primary’ dose are being invited for their second within the three month period - was six as beforehand.
Can you present your evidence?
 

danm14

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Do you have any evidence to suggest that immunsuppressed patients do gain a response based on non-MRNA vaccines? Blood tests and lots of data worldwide suggests the opposite. Those we received their third ‘primary’ dose are being invited for their second within the three month period - was six as beforehand.
I haven't got the first clue. I'm not a medical professional, I simply answered someone who asked what a "third primary" dose is.
 

Yew

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Back in 2020, we discussed the 'herd immunity threshold' as being 1-1/R0.

Random numbering for delta R0 as 5, and Omicron as 10 (to make the numbers easier), we'd expect to see a group from 80% to 90%. Are we seeing a short spike as we move between the two? I realise that immunity is a more complicated field, and our vaccines don't seem to be fully sterilising (given that we're seeing 95% antibody prevelance) but assuming the wave in South Africa isn't a measurement artefact, it's the only vaguely plausible situation I can think of.
 

21C101

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A "third primary" dose is given to people who are immunocompromised because of a belief that they need three doses to derive the benefit two doses gives to the general population.

The third dose is considered part of their original course (just like the two doses other people received), rather than a booster dose. They then receive a booster dose at the usual interval following their third dose.

I don't believe there is such a thing as a "fourth primary" dose - outside of some very specific situations (e.g. Novavax trial participants who opted for revaccination with Pfizer to travel abroad, and then got a booster) nobody in the UK should have received five doses of vaccine.

In any case, eligibility to keep a PCR test at home and receive antivirals by post is much wider than those who received third primary doses.
Thanks
 

Stephen42

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So, more good news as it looks increasingly likely that Omicron is indeed a less virulent variant compared to Delta, and we may reach a point in a matter of days where Chris Whitty and the Government might actually admit it.
It's likely tomorrow given the latest reports out of Edinburgh and Imperial.
But as others have said, if the Omicron variant was not fundamentally milder, why did South Africa report suddenly milder cases from the time when Omicron became dominant there, and why is a similar thing happening here a few weeks later?

Of course our immunity is getting greater all the time as more people get vaccinated and infected, and this is going to have the effect of reducing hospitalisations and deaths, and we have seen this gradually taking effect over a long period of time. But Omicron has caused a step change in hospitalisations that surely cannot be explained by immunity alone.
The difficulty with any new variant is being able to reliably compare data, the acquired immunity from vaccination/infection can be significant when comparing over waves. Even within the same time period the tail of one variant may infect a very different group to the start of another. For example in England early infections with Omicron (or more precisely S-Gene Target Failure) were 4 times less likely to be hospitalised, but the infections were in groups with lower hospitalisation rates so dropped to a non-significant 5% reduction after adjustment.

Performing those adjustments in a robust manner is difficult, particularly as reinfection is now an important part of the equation. The paper linked above with the 80% reduction has signs of a poor fit. This is another reason why early indications are often treated with caution, having analysis from multiple groups on different data sets gives more confidence that it's a real effect rather than an artifact of the methodology or data set.
 

brad465

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I can't get to it right now due to a paywall, but Fraser Nelson and Kate Andrews of The Spectator appear to have got hold of a SAGE memo that recently made the case for lockdown and was rejected. From what I'm seeing it could be an eye-opener at least on a par with Nelson vs Medley this weekend:


If anyone can share the article contents that would be very useful thank you.
 

Darandio

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If anyone can share the article contents that would be very useful thank you.

Done.

On Monday, Covid restrictions were rejected after the cabinet debated the issue robustly for the first time since the pandemic started. The Prime Minister said he’d revisit the decision, so the debate is very much still ongoing.


But it wasn’t just ministers meeting that day. Sage assembled its experts as well, with over 70 scientists and government officials in attendance. The minutes, seen by The Spectator, give an interesting summary of the official case for more lockdown restrictions.
Everyone is wrestling with two questions; if there are no more restrictions, how far will Omicron case numbers rise? And how will that translate into hospitalisations? If there is reason to believe that the NHS will be overwhelmed, this makes the case for more restrictions now. But if Omicron starts to level off and is so mild as to mean fewer hospitalisations than the earlier peak, as has been the case in South Africa, then restrictions could risk inflicting needless economic and social harm.
There is another twist to this. Sage is not the only outfit modelling Covid for the UK: there are now sophisticated independent forecasters as well. One is JP Morgan, whose extensive Covid research is being passed like samizdat papers between cabinet members who fear that Sage has a negative bias. ‘We anticipate the efficacy of boosters against hospitalisations holding up (with 90 per cent of over 65s already boosted) such that hospitalisations remain below 1,500 per day,’ JP Morgan says (the January peak was almost 4,000). In this scenario, British boosters save the day and Omicron is rebuffed by a wallof vaccinated people.


But the Sage memo paints a very different picture: of a vulnerable nation where more restrictions are needed for everyone quite quickly. Here are its main points:


1. Sage accepts that Omicron may have peaked in South Africa
In public, Sage officials talk about a ‘doubling time’ of Omicron to suggest that, without restrictions, its rise will be exponential. But it accepts that the virus is already levelling off in South Africa, the country with the most experience of Omicron which has not locked down. However, Sage says that assumptions about UK hospital admissions cannot be made from South Africa’s experience.
“‘The number of infections and hospitalisation in Gauteng appears to be declining. The reasons for this are not clear and it cannot be assumed that this will be sustained. Nor can it be assumed that the wave in the UK will follow a similar pattern, given the different populations and epidemiological situations.’


2. Sage says milder scenarios should ‘not be assumed for planning purposes’

The JP Morgan scenario had Omicron daily hospitalisations at 1,500. The PCCF model developed by Prof Philip Thomas (which predicted the third wave) suggests a peak of 2,800. Both envisage no more restrictions. But no such scenario appears in the Sage papers.
Indeed, ministers are explicitly told to forget about such scenarios ‘for planning purposes’. The latest Sage minutes suggest that a ‘range of values’ have been used to create scenarios for Omicron’s trajectory but that Omicron would need to be at least 90 per cent less severe than Delta to stop the NHS from being inundated.
“‘In the absence of further interventions or significant behaviour change, intrinsic severity would need to be greatly reduced (by around 90 per cent) for hospitalisations to not reach the levels of previous peaks unless the wave peaks early for other reasons, which should not be assumed for planning purposes.’


The 90 per cent figure appears to reference the University of Warwick’s modelling, which provides scenarios for 10, 20, 50, and 100 per cent severity, compared with Delta. Real-world data (the likes of which are not just coming in from South Africa) shows that Omicron is 80 per cent less likely to hospitalise; data from Denmark says 60per cent. They are the only two countries to have worked this out, and it is not yet known what emphasis can be put on variant severity, vaccines at work and natural immunity. But neither findings are mentioned in the Sage minutes. Instead there is simply a reference to ‘uncertainty’.


The final sentence – the optimistic scenarios and other factors that could influence the extent of admissions ‘should not be assumed for planning purposes’ – unnerves ministers who want to know: why not? What are they being given: a range of plausible projections or just a selection of worse-case ‘scenarios’? Neither Sage documents nor the accompanying interpretation makes this clear.


3. Sage say acting now stops longer measures later
The Sage document calls for ‘earlier interventions’ as well as a ‘short intervention… if introduced early enough’ to flatten the Omicron curve.


‘It continues to be the case that the earlier interventions happen the greater the effect they will have. Even a short intervention could reduce both peak and total admissions, particularly if introduced early enough. The main benefit of a short intervention would be in flattening the peak of admissions, and to allow more people to receive boosters. If measures are implemented later, when hospital admissions have risen significantly, measures may need to be in place for longer and may be too late to avert a period with very high admissions.’


4. Sage rejects the idea of more limited, ‘targeted measures’
Ministers are told that shielding and ‘targeted’ measures are not ‘effective’ compared to ‘population-wide’ measures. This suggests Sage leans more towards a circuit-breaker (a euphemism for lockdown) than less stringent interventions:


“‘Protective measures are important for the individual, and this is particularly the case for those who are at higher risk. However, measures targeted at more at-risk groups only (e.g. ‘shielding’) are not an effective substitute for population-wide measures if the aim is to reduce overall hospitalisation rates (high confidence).’


5. Sage cites ‘mental health’ as a reason to reject targeted measures

The document appears to look at one of the shielding options (that has been raised before by government): asking care home staff to shield, but not placing the same requirement on the rest of the population.


‘The group of people affected would be wider than just those the policy aimed to protect. For example, those coming into contact with residents (such as care home staff and visitors) may also need to reduce their contacts to prevent incursions of infections into the care home network. Reducing contacts may have significant negative impacts on the mental health and wellbeing of those asked to do so (high confidence). In addition, those who have previously been asked to shield may be reluctant to take similar steps again, reducing the effectiveness of such measures. If individuals are asked to reduce contacts more than the wider population, policies and messaging will need to consider potential reluctance and mental health impacts.’

6. Omicron is spreading within the NHS
“‘Hospitalisations with Omicron are increasing but the numbers remain uncertain. Pillar 1 testing data in Manchester indicate a doubling time of around 2–3 days for patients and staff testing positive for Omicron infection. This suggests that Omicron is getting into hospitals at a similar rate to its spread in the community’.
This certainly reflects data from London hospitals.


7. What Sage does not say: length of hospital stay
As each day passes, new data on Omicron comes rolling in but it’s striking how little of the more encouraging news is referenced. Take, for example, the length of stay in hospital. Sage has this to say:


‘Hospital occupancy will be affected by length of stay as well as admissions. Changes to treatment plans e.g., treating more patients at home, or increased use of antivirals, may affect admissions and occupancy. Occupancy scales approximately linearly with length of stay.’
In a ‘significant early finding’ South Africa found hospital stays with Omicron were closer to 2.8 days than 8.5 days, so this is a major variable which could have a game-changing effect on whether the NHS can cope. Again, ministers are given no hint of this in the Sage briefing note. Length of hospital stay was one of the variables that allowed JP Morgan to critique the LSHTM modelling and come up with a less alarming scenario where no more restrictions would be needed.


The document is phrased as if Sage is collectively making the case for lockdown: in reality Sage is a huge number of experts most of whom wish to provide advice but not lobby government for anything. But over the pandemic, Sage advice has tended to be edited and summarised by those inside government lobbying for more restrictions.
Nor are Sage attendees the decision-makers who ultimately decide whether or not we lock down. This morning, when talking about lockdown, Prof Graham Medley, chair of the Sage forecasters, said: ‘I am not making the decisions.’
It’s an important point: Prof Medley is an academic asked to model various scenarios by government officials, mindful of how risk lies on both sides. He has done more than most to open a window on how the whole process works. The academics on Sage are not responsible for how their advice is presented to ministers.
It’s cabinet that ultimately makes the call. The question they must ask is if they are being given the full picture by Sage, how to balance the risks involved and how many still-important questions need an answer before any decision to lock down again can be taken.
 

yorksrob

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If it's not the academics who are determined to make the case for lockdown and it's not the cabinet, who are the middle-men who seem determined to skew the advice ? The civil service ?
 

35B

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If it's not the academics who are determined to make the case for lockdown and it's not the cabinet, who are the middle-men who seem determined to skew the advice ? The civil service ?
It will be individuals, not organisations. Who precisely, I’ve no idea - and I’d not be surprised if they’re pretty well unknown.
 

yorksrob

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It will be individuals, not organisations. Who precisely, I’ve no idea - and I’d not be surprised if they’re pretty well unknown.

A transfer to the Ministry of Paperclips might be in order.
 

21C101

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It will be individuals, not organisations. Who precisely, I’ve no idea - and I’d not be surprised if they’re pretty well unknown.
One of them is very well known and as Chancellor of the Duchy of Lancaster was in a powerful position to get his way - Gove. Another was Hancock

Fortunately, both have been removed from pivotal positions. Although sadly Javid is already showing signs of institutional capture.
 

island

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It’s just three weeks to flatten the curve.
It’s just four more weeks.
It’s just a little while longer to protect the NHS.
It’s just a request to meet people outside.
It’s just two weeks at home when you come back from abroad.
It’s just to protect us all.
It’s just a mask.
It’s just a little delay.
It’s just a few more places to wear your mask.
It’s just changing the rules on two days’ notice.
It’s just a small limit on how many people can meet.
It’s just a few precautions as we go into winter.
It’s just 4 weeks to save Christmas.
It’s just a little while longer.
It’s just sacrificing Christmas to save Easter.
It’s just a little gesture during the coldest months.
It’s just safety to avoid importing Covid from abroad.
It’s just 12 days locked in a hotel room.
It’s just a few more weeks.
It’s just a chance to get more people vaccinated.
It’s just a precaution while cases rise.
It's just in case this variant is more transmissible.
It’s just temporary while we get boosters in arms.
 

brad465

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Now we seem to have widespread acceptance that Omicron is a much milder variant, I wonder if we are at the point, or very soon will be, where for anyone prone to vaccine side effects and not deemed vulnerable to covid, the side effects are/become worse than the actual virus?
 

david1212

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Nationally they are relatively flat, the problem is in London they are going up, now with 301 daily admissions in the last 24 hours. This matters because some reports suggest this rate is being used as a benchmark for future restrictions, if they exceed 400. This is despite the fact they peaked at nearly 1000 daily admissions in London last winter, and of course not everyone in hospital with covid actually went there with it.

I would hope that data from across the country is being used and particularly an analysis of the ratio of Omicron infections and increase in hospital admissions.

The tiers system had lots of flaws but bringing in Englandwide restrictions based purely on London hospital admissions would not be reasonable. Likewise if expanded to just the largest cities rather than nationwide.
 

yorkie

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Now we seem to have widespread acceptance that Omicron is a much milder variant, I wonder if we are at the point, or very soon will be, where for anyone prone to vaccine side effects and not deemed vulnerable to covid, the side effects are/become worse than the actual virus?
I think almost anyone (who is not in a vulnerable group) who has had two or more exposures to antigen with at least a 6 month gap between 1st and last exposure is probably in that position now.

If anyone has not yet been boosted and has not had an infection and has had 2 doses but with a shorter gap between doses than 6 months, I would encourage them to get boosted (especially if they had 2 doses of AZ; not because AZ is in any way inferior - I don't agree with anyone who makes that claim - but because there is good evidence that a combination of viral vector and mRNA doses gives enhanced protection over and above just one or the other) but other than that, we should be done. (The situation may change in a few months or years time depending on virus evolution and vaccine development)

This is just my opinion but it is based on doing a fair amount of research.
 

Eyersey468

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It’s just three weeks to flatten the curve.
It’s just four more weeks.
It’s just a little while longer to protect the NHS.
It’s just a request to meet people outside.
It’s just two weeks at home when you come back from abroad.
It’s just to protect us all.
It’s just a mask.
It’s just a little delay.
It’s just a few more places to wear your mask.
It’s just changing the rules on two days’ notice.
It’s just a small limit on how many people can meet.
It’s just a few precautions as we go into winter.
It’s just 4 weeks to save Christmas.
It’s just a little while longer.
It’s just sacrificing Christmas to save Easter.
It’s just a little gesture during the coldest months.
It’s just safety to avoid importing Covid from abroad.
It’s just 12 days locked in a hotel room.
It’s just a few more weeks.
It’s just a chance to get more people vaccinated.
It’s just a precaution while cases rise.
It's just in case this variant is more transmissible.
It’s just temporary while we get boosters in arms.
Exactly, it feels like this will never end.
 
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